Washington County, Pennsylvania - Francis Peake was born about 1780 in the territory that was later to become Washington County, Pennsylvania, the 12th child of Thomas Peake and Lettice Moseley.
Campbell County, Kentucky - Francis Peake married Euphy Glore on 17 January 1804 in Campbell County, Kentucky. One son, St. Clair Peake, was born of this marriage. St. Clair is identified as the sole heir of Euphy Peake in the 1835 will of her father Adam Glore. Another child, daughter Ufa Peake, was born to Francis Peake in 1810; therefore it is assumed that Euphy Glore was deceased by 1810 and that Francis had remarried by that date.
Clermont County, Ohio - Francis Peake was mentioned in court records in Clermont County about 1812 and was enumerated there in 1820 with a wife and six children. It is presumed, but not yet proven, that this was his second wife named Lucinda, mother of Eupha Peake.
Preble County, Ohio - By 1830 Francis Peake was in Preble County, Ohio, along with many members of the Frame family. Daughter Elizabeth Peake married Newton Frame in 1829 in Preble County, Ohio; daughter Ufa Peake married John Frame in Preble County in 1827.
Porter County, Indiana - The Frame family, including the Peake daughters, moved further west to establish homes in Porter County, Indiana. Newton Frame and wife Elizabeth Peake was in Porter County by 1834; John Frame and wife Ufa Peake arrived in 1849. By 1850 Francis Peake and his wife Lucinda were also living in Porter County, Indiana. Francis was an 80 year old widower in the 1860 census. In 1880, son Hubbard Peake was living in Portage Township, Porter County with his wife Ann Harrison, three children, and one grandson.